Burrill & Easter proposed identity of AF-1 in the adult:
Suprachiasmatic nucleus (SCN) & Parvocellular preoptic nucleus, posterior part (nPPp).
Baier & Wullimann proposed identity of AF-1 in the adult: Suprachiasmatic nucleus/Nucleus suprachiasmaticus (SCN) (Baier & Wullimann, 2021).
Schematic showing the approximate location of AF-1 in a 6dpf zebrafish. The optic tract is labelled in the Tg(atoh7:RFP) transgenic line and position of AFs are based on the data from Robles (2014).
“ We have identified AF-1 as the presumptive nSCN and the presumptive nPPp because, similar to the nSC, AF-1 was located adjacent and dorsocaudal to the optic chiasm and was bilaterally innervated, the ipsilateral optic axons having redecussated dorsal to the optic chiasm. The caudal extension of AF-1 observed in the 6-7 day larvae is assumed to be a projection to the presumptive nPPp which is located caudal to the nSC in some adult cypriniformes” (Burrill & Easter, 1996)
AF-1 is preferentially innervated by Retinal Ganglion Cells (RGCs) located in the ventral retina (Robles et al., 2014).
AF-1 is preferentially innervated by Retinal Ganglion Cells (RGCs) located in the ventral retina (Robles et al., 2014).
Publications
Moore HA, Whitmore D (2014)
Circadian Rhythmicity and Light Sensitivity of the Zebrafish Brain.
PLoS ONE 9(1): e86176. https://doi.org/10.1371/journal.pone.0086176
Robles, E., Laurell, E., Baier, H. (2014)
The Retinal Projectome Reveals Brain-Area-Specific Visual Representations Generated by Ganglion Cell Diversity.
Current biology : CB. 24(18):2085-96.
Burrill JD & Easter Jr SS
Development of the Retinofugal projections.
J Comp Neurology, 2004 pp.1-18.