The zebrafish is a small tropical fish that has become one of the favoured animal model systems for research in many areas including embryonic development, genetic analyses of disease, neural circuit function and behaviour. One reason for this popularity is that zebrafish embryos are optically transparent and genetically tractable making them ideally suited for studies of cell and tissue behaviour and function. Zebrafish also exhibit sleep, social, hunting and other complex behaviours and progress in understanding the neuroanatomy of the brain is facilitating studies of the neural circuits mediating these behaviours.
On this site, you can learn about the wide range of research projects at UCL that use zebrafish and see many beautiful images and movies from these projects. We appreciate that not all our visitors are trained scientists and so we have public outreach pages that help to explain what we do.
There are many research groups using zebrafish for research at UCL and you can find out about some of them here, or continue reading about Zebrafish at UCL.
Zebrafish research at UCL is supported by a team of core staff, who you can read about here.
Many of our images are available for download from Wellcome Images.
Simply search the collection for 'Zebrafish'. All images and movies are copyright of UCL Zebrafish Group please request permission before using.
We believe that science is meant to be shared, and not just with other scientists.
Below are a few details of some of the activities in which Zebrafish UCL labs participate in to disseminate science to the public.
A-Level Placements at Zebrafish UCL
The 2018 application deadline has now passed for Wilson/Rihel/Bianco/Tada Lab A-Level Work Experience Program for 2018. Click here for more information about the programme.
For a full list of Zebrafish UCL publications by year click here, or choose a year below. You can also visit our publication summaries page to find summaries of papers that need less scientific knowledge to understand.
Gaia Gestri, Naiara Bazin-Lopez, Clarissa Scholes and Stephen W. Wilson (2018)
Cell Behaviors during Closure of the Choroid Fissure in the Developing Eye.
Frontiers in Cellular Neuroscience. doi.org/10.3389/fncel.2018.00042
Anna M. Krasnow 1, Marc C. Ford , Leonardo E. Valdivia, Stephen W. Wilson and David Attwell (2018)
Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo.
Nature Neuroscience .doi:10.1038/s41593-017-0031-y
Singh C, Rihel J, and Prober DA (2017).
Neuropeptide Y Regulates Sleep by Modulating Noradrenergic Signaling.
Current Biology, doi.org/10.1016/j.cub.2017.11.018
Schoppik D, Bianco IH, Prober DA, Douglass AD, Robson DN, Li JMB, Greenwood JSF, Soucy E, Engert F, Schier AF.(2017)
Gaze-stabilizing central vestibular neurons project asymmetrically to extraocular motoneuron pools.
J Neurosci. pii: 1711-17. doi: 10.1523/JNEUROSCI.1711-17.2017
Wolf S, Dubreuil AM, Bertoni T, Böhm UL, Bormuth V, Candelier R, Karpenko S, Hildebrand DGC, Bianco IH, Monasson R, Debrégeas G.(2017)
Sensorimotor computation underlying phototaxis in zebrafish.
Nat Commun. 8:651. doi: 10.1038/s41467-017-00310-3.
Hildebrand DGC, Cicconet M, Torres RM, Choi W, Quan TM, Moon J, Wetzel AW, Scott Champion A, Graham BJ, Randlett O, Plummer GS, Portugues R, Bianco IH, Saalfeld S, Baden AD, Lillaney K, Burns R, Vogelstein JT, Schier AF, Lee WA, Jeong WK, Lichtman JW, Engert F. (2017)
Whole-brain serial-section electron microscopy in larval zebrafish.
Chen S, Reichert S, Singh C, Oikonomou G, Rihel J*, and Prober DA* (2017).
Light-dependent regulation of sleep/wake states by prokineticin 2 in zebrafish.
Neuron. http://dx.doi.org/10.1016/j.neuron.2017.06.001. *co-corresponding
Van Lessen M, Shibata-Germanos S, van Impel A, Hawkins TA, Rihel J, and Schulte-Merker S (2017).
Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development.
eLife DOI: http://dx.doi.org/10.7554/eLife.25932
Barlow IL and Rihel J (2017).
Zebrafish sleep: from geneZZZ to neuronZZZ. Current Opinion in Neurobiology, 10.1016/j.conb.2017.02.009
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