The Tuschl Lab uses manganese transporter mutant zebrafish as models for manganese overload/deficiency in order to dissect how metal dyshomeostasis disrupts neurons, synapses and circuit function with the view to identifying new therapeutic targets. In addition, we are working to develop a novel, orally bioavailable Mn chelator to improve treatment for disorders associated with Mn neurotoxicity.
This role will provide technical support and research related activities by assisting with experimental procedures and analysis of results within Zebrafish UCL (http://zebrafishucl.org/wilson-lab; http://zebrafishucl.org/tuschl). The successful applicant will assist the lab with maintenance of various zebrafish lines, working on a daily basis with adult fish. The post is available from 1 January 2024 until 31 December 2024 as a fixed term contract. For more information about the role, please contact Prof Steve Wilson (s.wilson@ucl.ac.uk) or Dr Karin Tuschl (k.tuschl@ucl.ac.uk).