Rhodopsin

Rhodopsin

ABOUT THIS ANTIBODY

Anti-Rhodopsin labels rod photoreceptors

Rhodopsin is a G-protein coupled receptor and has been found to be expressed in the rod photoreceptors. Its antibody labels rod photoreceptors (Intartaglia et al., 2022). It stained photoreceptors well in the killifish.

Rabbit Polyclonal anti-Rhodopsin (Hyde lab, Cat#1d4, dilution 1:100)

image

by Ryan MacDonald

Section of killifish retina anti-Rhodopsin in green, zpr-1 in magenta and DAPI in blue

Image by Ryan MacDonald

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labels these retinal cell types

Rod photoreceptors

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key publications

Intartaglia D, Giamundo G, Naso F, Nusco E, Di Giulio S, Salierno FG, Polishchuk E and Conte I. 2022. Induction of autophagy promotes clearance of RHOP23H aggregates and protects from retinal degeneration. Frontiers in Aging Neuroscience. 14:1-14.

Zpr-1

Zpr-1

ABOUT THIS ANTIBODY

Anti-Zpr-1 labels double cone photoreceptors

Zpr-1 antibody detects an unknown antigen specific to double cones in zebrafish (Yin et al., 2012). Great photoreceptors staining was found in the killifish.

Mouse Monoclonal anti-Zpr-1 (ZIRC, Cat#AB_10013803, dilution 1:1000)

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Section of killifish retina anti-zpr-1 in magenta, anti-Rhodopsin (ID4) in green and DAPI in blue

Image by Ryan MacDonald

Section of 3 mpf female killifish sodium citrate antigen retrieval anti-Zpr-1 in magenta and DAPI in blue

Image by Eva-Maria Breitenbach

PS = photoreceptors, ONL = outer nuclear layer, OPL = outer plexiform layer, INL = inner nuclear layer, IPL = inner plexiform layer

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labels these retinal cell types

Double cone photoreceptors

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key publications

Yin J, Brocher J, Linder B, Hirmer A, Sundaramurthi H, Fischer U and Winkler C. 2012. The 1D4 antibody labels outer segments of long double cone but not rod photoreceptors in zebrafish. Investigative Ophthalmology & Visual Science, 53:4943-4951.