Schematic showing the position of the lens in sagittal, horizontal and coronal sections through the zebrafish brain.
Based on the anatomical segmentation of 3 day old zebrafish larval brain by Thomas Müller, Olaf Ronneberger, Wolfgang Driever and colleagues. For details see Ronneberger et al., Nat. Meth. 2012 and http://vibez.informatik.uni-freiburg.de
Abbreviations: GCL, ganglion cell layer; INL, inner nuclear layer ; ipl, inner plexiform layer ; ONL, outer nuclear layer ; opl, outer plexiform layer; RPE, retinal pigmented epithelium.
Description
Upon neural retina specification, signals from the neural retina induce lens fate in the overlying surface ectoderm. The lens placode then invaginates to give rise to the lens vesicle, which buds out at around 24hpf. The lens vesicle keeps growing throughout adulthood and fibre cells differentiation is maintained from a pool of undifferentiated proliferating epithelial cells located at the most anterior region of the vesicle.
Ontology
is part of: eye
has parts:
Transgenic Lines/Antibodies that label this brain region
Key Publications