Bipolar Cells

Bipolar Cells

Bipolar cells are interneurons that transmit information from photoreceptors to the inner retina.  Bipolar cells are classified by three main criteria:  the type of photoreceptor that provides input, dendritic and axonal morphologies, and the polarity of their responses (e.g., depolarizing or hyperpolarizing). 

Schematic depicting the different cell types and layers that make up the neural retina in an adult zebrafish adapted from Baden et al., 2019. Bipolar cells have their cell bodies in the inner nuclear layer. Their processes span the inner nuclear layer synapsing with horizontal cells and rods and cones in the outer plexiform layer and relaying their signals to amacrine and RGCs via connections in the inner plexiform layer.