Tg(atoh7 :gapRFP)cu2Tg

About

 atonal bHLH transcription factor 7 is turned on in retinal ganglion cells as they transition from proliferating neuroblast to differentiated neuron. The atoh7 promoter in this transgenic line drives the expression of a membrane tagged version of RFP so the axons of the RGCs are also labelled so the optic nerve and tract projecting from the retina to the optic tectum can be distinguished.

---

External Links:

 ZFIN

Lab or Origin: Bill Harris Lab

---

Expressed in: 

Retinal ganglion cells, cilliary marginal zone, retina, optic nerve. optic tract, optic tectum.  

---

Key Publications

 Zolessi, F.R., Poggi, L., Wilkinson, C.J., Chien, C.B., and Harris, W.A. (2006)
Polarization and orientation of retinal ganglion cells in vivo.
Neural Development. 1:2.

sox3h10:EGFP

About

---

sox3h10:EGFP 5dpf lateral

pallial neuron in sox3h10 lateral view at 5dpf

Cilliary marginal zone expression in sox3h10:EGFP

lateral view of retina at 5dpf

Cilliary marginal zone expression in sox3h10:EGFP

lateral view of retina at 5dpf

sox3h10:EGFP and tubulin dorsal view at 5dpf

showing expreession in pineal and habenulae.

sox3h10:EGFP and tubulin dorsal view of hindbrain at 5dpf

sox3h10:EGFP dorsal view of hindbrain at 5dpf

sox3h10:EGFP dorsal diencephalon at 5dpf

sox3h10:EGFP and tubulin Lateral view of hindbrain

5dpf

sox3h10:EGFP and tubulin Lateral view

5dpf

sox3h10:EGFP and tubulin Lateral view 2dpf

sox3h10:EGFP Lateral view at 2dpf

sox3h10:EGFP and tubulin dorsal view 2dpf

sox3h10:EGFP dorsal view 2dpf

External Links:

 ZFIN

Lab or Origin: Tom Becker Lab

---

Expressed in: 

 ciliary marginal zone of retina,pallium, pineal, habenula, hindbrain

---

Key Publications

 Navratilova, P., Fredman, D., Hawkins, T.A., Turner, K., Lenhard, B., and Becker, T.S. (2009) Systematic human/zebrafish comparative identification of cis-regulatory activity around vertebrate developmental transcription factor genes. Developmental Biology. 327(2):526-540.