4C4

ABOUT THIS ANTIBODY

Anti-4C4 labels microglia

4C4 antibody has been found to bind to microglia in the zebrafish retina (Raymond et al., 2006). In the killifish 4C4 labelled Müller glia in the ganglion cell layer, particularly the endfeet. Further, staining was found in the photoreceptors.

Mouse Monoclonal anti-4C4 (Merck, Cat#92092321, dilution 1:150)

image

by Eva-Maria Breitenbach

Section of 4 mpf male killifish sodium citrate antigen retrieval anti-4C4 in magenta and DAPI in blue

PS = photoreceptors, ONL = outer nuclear layer, OPL = outer plexiform layer, INL = inner nuclear layer, IPL = inner plexiform layer, GCL = ganglion cell layer


labels these retinal cell types

Microglia


key publications

Raymond PA, Barthel LK, Bernardos RL and Perkowski JJ. 2006. Molecular characterization of retinal stem cells and their niches in adult zebrafish. BMC Developmental Biology. 6:1-17.