Ribeye-A

Ribeye-A

ABOUT THIS ANTIBODY

Anti-Ribeye-A labels synapses

Ribeye-A protein is a scaffolding component in the ribbon where vesicles are tethered, its antibody has been found to label synapses (Shankhwar et al., 2022). Many spots were found across the outer plexiform layer, inner nuclear layer, inner plexiform layer and ganglion cell layer in the killifish.

Rabbit Polyclonal anti-Ribeye-A (Nicolson lab, Cat#Custom, dilution 1:100)

images

Section of young killifish retina anti-Ribeye-A in green and DAPI in blue

Image by Ryan MacDonald

Section of killifish retina anti-Ribeye-A in green, anti-GS in magenta and DAPI in blue

Image by Ryan MacDonald

Section of 4 mpf male killifish sodium citrate antigen retrieval anti-Ribeye-A in green and DAPI in blue

Image by Eva-Maria Breitenbach

PS = photoreceptors, ONL = outer nuclear layer, OPL = outer plexiform layer, INL = inner nuclear layer, IPL = inner plexiform layer, GCL = ganglion cell layer

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labels these retinal cell types

Synapses

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key publications

Shankhwar S, Schwarz K, Katiyar R, Jung M, Maxeiner S, Südhof TC and Schmitz F. 2022. RIBEYE B-Domain Is Essential for RIBEYE A-Domain Stability and Assembly of Synaptic Ribbons. Frontiers in Molecular Neuroscience. 15:1-26.