Tumor protein P53
ABOUT THIS ANTIBODY
Anti-P53 labels apoptosis
Tumor protein P53 is a sequence specific transcription factor which is being activated when cells are under stress. P53 antibody stains cell death in mice (Dong et al., 2019). In killifish it labelled one cell in the outer nuclear layer (white arrow).
Rabbit Polyclonal anti-P53 (Proteintech, Cat#21891-1-AP, dilution 1:100)
image
by Eva-Maria Breitenbach
Section of 4 mpf female killifish sodium citrate antigen retrieval anti-P53 (green) and DAPI (blue)
PS = photoreceptors, ONL = outer nuclear layer, OPL = outer plexiform layer, INL = inner nuclear layer, IPL = inner plexiform layer, GCL = ganglion cell layer
labels these retinal cell types
Apoptosis
key publications
Dong S, Ji J, Hu L and Wang H. 2019. Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration. Life Sciences. 227:20-29.