Parvalbumin (PV)

ABOUT THIS ANTIBODY

Anti-PV labels amacrine cells

Parvalbumin (PV) antibody binding to parvalbumin which is a regulator of neuronal intracellular calcium dynamics and found to stain amacrine cells in zebrafish (Ahmed, Kojima and Masai, 2022). In the killifish it stained cells in the inner nuclear and ganglion cell layer; and linear speckled staining in the inner nuclear, plexiform and ganglion cell layer.

Mouse Monoclonal anti-PV (Sigma, Cat#P3088, dilution 1:200)

imageS

Section of killifish retina anati-PV in magenta and DAPi in blue

Image by Ryan MacDonald

Section of killifish retina anti-PV in magenta, anti-Sox2 in green and DAPI in blue

Image by Ryan MacDonald

labels these retinal cell types

Amacrine cells

key publications

Ahmed M, Kojima Y and Masai I. 2022. Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation. eLife. 11:1-34.