New Nature paper from the Rihel Lab based on the PhD work of Anya Suppermpool
Synaptic Nightlife by Anya Suppermpool
During sleep, the brain weakens the new connections between neurons that had been forged while awake – but only during the first half of a night’s sleep, according to a new study in fish by UCL scientists.
Read more about this exciting study in this UCL press release.
or read the whole study at Nature!
New study from the Tuschl Lab: Our manuscript on manganese neurotoxicity in wild-type zebrafish is out – affecting morphology, neurogranin expression and locomotor behaviour! Collaboration between UCL and Dr Monica Folgueira’s group at University of A Coruña, Spain. From Anabel’s work during her lab visit in spring 2022. https://www.mdpi.com/1422-0067/25/9/4933
The L’Oréal-UNESCO For Women in Science partnership aims to help empower more women scientists to achieve scientific excellence and participate equally in solving the great challenges facing humanity.
Mie Wong has been highly commended for the For Women In Science Rising Talent Life Sciences Award. Congratulations, Mie!
Gina is a BBSRC LiDO student and Marybelle is a UCL Excellence Scholar. If you would like to read more about thier projects and interests click on the images below.
Marybelle Cameron-Pack
Gina Gilpin
Golsana Haghdousti is the first student in the Tuschl lab to successfully pass her upgrade from MPhil to PhD – massive congratulations!!!
This year the lab celebrated 2023 with Christmas lunch at an Italian restaurant before heading off to axe throwing. Everyone had a great time and managed to leave with all of their fingers.
Ryan turned 40 this year. So the lab bought him very useful tools for his old age. Manuela also made him his favourite type of cake - a Muller glia cake.
Ola earned her Master's degree in Neurosciences from Vrije Universiteit Amsterdam and conducted research for her master's thesis at Brigham and Women's Hospital at Harvard Medical School. There, she focused on developing patient-specific stem cell models to assess the safety and efficacy of antisense oligonucleotide therapy for dentatorubral-pallidoluysian atrophy (DRPLA).
Driven by a keen interest in retinal biology and in vivo disease modeling, she joined the MacDonald Lab as a PhD student in October 2023. Her project aims to introduce the African turquoise killifish as a model for understanding molecular and cellular dysfunctions underpinning vision loss with ageing.
Outside the lab, Ola enjoys hiking trips, exploring London and watching cinema classics.
Lewis has joined the Bianco lab as a Research Technician. Welcome!
Aanandita Kothurkar wins the prize for the best MSc GHD dissertation of the year 2021/22 – huge congratulations!
The Tuschl Lab uses manganese transporter mutant zebrafish as models for manganese overload/deficiency in order to dissect how metal dyshomeostasis disrupts neurons, synapses and circuit function with the view to identifying new therapeutic targets. In addition, we are working to develop a novel, orally bioavailable Mn chelator to improve treatment for disorders associated with Mn neurotoxicity.
This role will provide technical support and research related activities by assisting with experimental procedures and analysis of results within Zebrafish UCL (http://zebrafishucl.org/wilson-lab; http://zebrafishucl.org/tuschl). The successful applicant will assist the lab with maintenance of various zebrafish lines, working on a daily basis with adult fish. The post is available from 1 January 2024 until 31 December 2024 as a fixed term contract. For more information about the role, please contact Prof Steve Wilson (s.wilson@ucl.ac.uk) or Dr Karin Tuschl (k.tuschl@ucl.ac.uk).
Summer in London now seems to be well and truely over, but the lab did manage to get together for a lovely BBQ on the last sunny (and very hot) Saturday of the season.
Photo taken by Joanna (on a real, film camera).
The Wellcome Trust sent a film crew to the zebrafish labs to find out more about the work the Wilson and Bianco labs are doing to understand more about brain asymmetry.
The MacDonald lab went out to thank the 3 Bachelor students, Huanlin, Hiba and Nicole, who had joined the lab over the summer.
Six members of the academic staff of the Institute of Ophthalmology were promoted this year, amongst them is our PI Ryan MacDonald you got promoted to Associate Professor. Congratulations!
Click here to find out more.
Manuela Lahne, Ryan MacDonald and Gregory Patient went to the annual European Zebrafish Meeting. Gregory presented his work with Iterative Bleaching Extends Multiplexity (IBEX) which is a highly multiplexed immunohistochemistry technique which allows multiple rounds of immunohistochemistry to be performed on a single tissue sample. More information can be found here.
Welcome Huanlin, Hiba and Nicole to the MacDonald lab. We are excited that you have joined us.
We would like to welcome Dr Artur R Fernandes to the MacDonald lab. He is here as a visiting Postdoc.
We’re really proud of Asaph Zylbertal who won the UCL Early Career Neuroscience Prize (Advanced category) for his beautiful study about how recurrent interactions in the optic tectum help explain the interactions between sensory input and the brain’s internal state.
Here’s Asaph giving his talk at the UCL Neuroscience Symposium and receiving the award from Prof Trevor Smart.
Check out the paper here: doi.org/10.7554/eLife.78381
Natalia, Manuela and Xhuljana presented posters at the annual IoO ECR Symposium. Natalia won the best communication poster award and second runner-up scientific poster award. Congratulations!
